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Integrin β3: structural functions, tumour microenvironment regulatory roles and targeted intervention strategies
Structural roles of Integrin β3, its influence on the tumor environment, and targeted treatment approaches
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Abstract
Integrin β3 (ITGB3) is linked to critical processes in tumor progression, including invasion and metastasis.
- Dysregulated ITGB3 expression activates pathways associated with cell movement and growth.
- Key malignant processes influenced by ITGB3 include angiogenesis and immune evasion.
- ITGB3 is identified as a valuable biomarker for early cancer diagnosis and prognosis.
- Therapeutic strategies targeting ITGB3 include small-molecule inhibitors and monoclonal antibodies.
- Traditional Chinese Medicine formulations may provide unique regulatory benefits for targeting ITGB3.
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