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Abstract
The meta-analysis included 15 randomized controlled trials with 1,142 patients (2,284 eyes).
- Intense pulsed light (IPL) therapy may significantly reduce scores on the ocular surface disease index (OSDI), standard patient evaluation of eye dryness (SPEED), and artificial tear usage.
- IPL therapy is associated with improved tear film stability, indicated by increased tear break-up time (TBUT) and noninvasive tear break-up time (NIBUT).
- Improvements in meibomian gland quality (MGQ) and expression (MGX) were noted, along with decreased corneal fluorescein staining (CFS).
- Compared to meibomian gland expression alone, IPL combined with MGX showed marked decreases in SPEED, CFS, and tear meniscus height (TMH), while increasing TBUT.
- No significant differences were found between IPL combined with MGX and MGX alone for OSDI, MGQ, or MGX outcomes.
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