Full text is available at the source.
Intracellular potassium levels orchestrate circadian rhythmicity and cell division
Inside-cell potassium levels control daily rhythms and cell growth
AI simplified
Abstract
Intracellular potassium levels regulate the period and phase of clock gene expression rhythms.
- Disruption of circadian rhythms is associated with increased risks of infectious diseases, metabolic disorders, and cancer.
- Potassium concentrations influence the timing of cellular circadian rhythms and cell cycle events.
- Manipulating potassium levels inhibits cell proliferation in a manner that depends on the circadian phase.
- Potassium rhythms are essential for maintaining the connection between circadian and cell proliferation rhythms.
- This research establishes potassium as a key factor linking cellular processes to circadian cycles.
AI simplified