Intracranial EEGs evidenced visual object processing in the human medial temporal lobe subregions

The perirhinal cortex (PRC) was more strongly activated than the parahippocampal cortex (PHC) or hippocampus (HPC) approximately 100 ms after an object stimulus.

• The PRC, PHC, and HPC are activated within the broad-gamma band during visual object encoding.
• Strong bidirectional interactions were observed between the PRC and both the PHC and HPC in the low-frequency band.
• Interactions between the PHC and HPC were not significant.
• These findings highlight the PRC's core role in visual object information encoding.
• The study provides new insights into the interactions of the PHC with the PRC, which may extend beyond traditional theories of visual processing.

AI simplified