Journal of Occupational and Environmental MedicineOct 17, 2025

Ketamine Therapy Results for First Responders with Multiple Mental Health Conditions

Psychedelic Science Weekly Brief ↗PubMed ↗DOI ↗

Updated Dec 29, 2025

Abstract

Six firefighters with PTSD participated in a 12-week ketamine-assisted therapy program.

KAT may improve sleep issues.
Participants reported a changed relationship with music.
There could be increased tolerance for sensory stimuli.
Time perception may change for those receiving KAT.
Benefits may extend beyond just reducing PTSD symptoms.

Simplified

OBJECTIVE: Many first responders deal with mental health challenges due to significant work-related stress. Ketamine-assisted therapy (KAT) has been shown to alleviate the symptoms and improve the lives of those living with PTSD. This qualitative case study explores the impacts of KAT on the firefighters beyond the initial alleviation of their PTSD symptoms.

METHODS: Six firefighters who were diagnosed with PTSD participated in a 12-week KAT program, which combined several virtual Community of Practice meetings as well as in-person small group ketamine sessions. Participants were interviewed about their journey to receiving treatment, and a follow-up survey was also sent.

RESULTS: The novel themes that emerged from this study include: improvement in sleep problems, relationship to music, improved tolerance for sensory stimuli, and changes in time perception.

CONCLUSIONS: KAT may provide meaningful benefits beyond symptom reduction.

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Ketamine Therapy Results for First Responders with Multiple Mental Health Conditions

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