The international journal of neuropsychopharmacology

Ketamine's effects on brain activity and therapy links vary in treatment-resistant depression, PTSD, and OCD

Updated

Abstract

All neurotic disorders may respond quickly to low dose ketamine (0.5-1.0 mg/kg I.M.), even when resistant to conventional treatment.

  • Neurotic disorders include major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and specific phobia.
  • Each disorder has a unique response to various pharmaceutical treatments.
  • Low doses of ketamine have been shown to induce rapid responses in these disorders.
  • This response may occur despite resistance to traditional treatment options.

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