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Abstract
Ketamine may enhance smoking cessation efforts when combined with motivational enhancement therapy.
- Tobacco use is a major preventable cause of illness and death.
- Current treatments for tobacco use disorder have only modest effectiveness.
- Ketamine acts on glutamate receptors and may promote brain adaptability.
- Combining ketamine with motivational enhancement therapy could support behavioral treatments.
- This combination may improve cognitive flexibility and psychological resilience in individuals trying to quit smoking.
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