Full text is available at the source.
Abstract
The review highlights the potential influence of metabolites of lactic acid bacteria (metLABs) on brain functions through the microbiota-gut-brain axis.
- MetLABs may affect neuron signaling in both the enteric and central nervous systems.
- There is a focus on how metLABs can impact mitochondrial function and neuronal development.
- Exposure to metLABs could lead to the release of neurotrophic factors in cells and the host.
- Clinical evidence is limited, but some studies suggest that metLAB-containing fermented foods may enhance brain functions.
- Two ongoing clinical trials are examining whether probiotic interventions can slow the progression of Alzheimer's disease.
Simplified