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Abstract
A small randomized controlled trial tested the efficacy of lemborexant in improving daytime sleep among night shift workers.
- Sleep difficulties are prevalent in shift workers, potentially due to misalignment between sleep preferences and circadian rhythms.
- Current treatments for enhancing daytime sleep in shift workers are limited.
- Lemborexant, a dual orexin receptor antagonist, targets the wakefulness-promoting receptors linked to the biological clock.
- The trial aimed to determine whether lemborexant could be more effective than placebo for daytime sleep improvement.
Simplified
Circadian Biology