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Abstract
Hepatic alkaline phosphatase released from diseased liver may suppress intestinal stem cell differentiation into GLP-1-secreting L-cells.
- Fatty liver disease is associated with hyperglycemia.
- The study identifies a potential mechanism linking liver dysfunction to intestinal processes.
- Intestinal stem cells may be affected by factors released from the liver.
- This mechanism suggests a new route of communication between the liver and intestines.
Simplified