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Long COVID: pathophysiological factors and abnormalities of coagulation
Long COVID: body changes and blood clotting problems
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Abstract
Approximately 65 million individuals worldwide are affected by Long COVID, which follows acute COVID-19 infection in about one in ten cases.
- Long COVID is associated with prolonged symptoms resulting from several underlying mechanisms.
- Viral factors such as persistence and reactivation of SARS CoV-2 may contribute to the condition.
- Host factors including chronic inflammation and immune dysregulation could play a role in Long COVID.
- Downstream impacts like tissue damage and dysregulation of the autonomic nervous system are observed.
- The condition is characterized by thrombotic endothelialitis and inflammation of blood vessels, affecting multiple organ systems.
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