Trends in endocrinology and metabolism: TEM

Long COVID: body changes and blood clotting problems

Updated

Abstract

Approximately 65 million individuals worldwide are affected by Long COVID, which follows acute COVID-19 infection in about one in ten cases.

  • Long COVID is associated with prolonged symptoms resulting from several underlying mechanisms.
  • Viral factors such as persistence and reactivation of SARS CoV-2 may contribute to the condition.
  • Host factors including chronic inflammation and immune dysregulation could play a role in Long COVID.
  • Downstream impacts like tissue damage and dysregulation of the autonomic nervous system are observed.
  • The condition is characterized by thrombotic endothelialitis and inflammation of blood vessels, affecting multiple organ systems.

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Funding

Competing interests

Declaration of interests None are declared by the authors.
PubMed

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