Clinical and experimental medicine

Long non-coding RNAs linked to treatment resistance in multiple myeloma, from molecular details to clinical use

Updated

Abstract

(lncRNAs) may play significant roles in the biology of multiple myeloma (MM).

  • lncRNAs are implicated in key molecular processes such as regulating gene expression and influencing disease progression in MM.
  • These RNA molecules may affect treatment response by interacting with cellular signaling pathways like PI3K/Akt and STAT3.
  • Emerging treatment strategies targeting lncRNAs include RNA-based therapeutics and CRISPR/Cas9 technology.
  • The potential of lncRNAs as biomarkers and therapeutic targets in MM is highlighted, suggesting avenues for future research.

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Funding

Competing interests

Declarations. Competing interests: The authors declare no competing interests. Consent to participate: Not applicable. Consent for publication: Not applicable. Clinical trial number: Not applicable.
PubMed

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