Loss of functional cryptochrome 1 reduces robustness of 24-hour behavioral rhythms in monarch butterflies

Feb 9, 2024iScience

Loss of a key biological clock protein weakens daily activity patterns in monarch butterflies

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Abstract

Loss of functional dpCRY1 in monarch butterflies reduced the amplitude and altered the phase of adult eclosion rhythms.

  • The monarch butterfly uses both visual input and the blue-light photoreceptor dpCRY1 for entraining its circadian rhythms.
  • Disruption of dpCRY1 functionality led to changes in molecular circadian rhythms in the brain.
  • Robust circadian rhythms could be restored through temperature cycle entrainment in dpCRY1 mutants.
  • Rhythmic flight activity was found to be less consistent in dpCRY1 mutants.
  • Visual impairment in dpCRY1 mutants affected their flight suppression during nighttime.

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