Frontiers in immunology

Gentle low-frequency mechanical stimulation may reduce depression-like behavior in rats by affecting gut-brain communication

Updated

Abstract

Depression is associated with dysregulation of neuroendocrine, immune, and gut-brain axis pathways.

  • Dysregulation in these pathways may contribute to the symptoms of depression.
  • Exercise has been identified as an effective non-pharmacological intervention for depression.
  • Poor motivation and fatigue can limit adherence to exercise in patients with depression.

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