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Low-Level Inflammation, Immune Response, and Brain-Gut Communication in Irritable Bowel Syndrome
Updated
Abstract
is associated with low-grade chronic inflammation.
- The etiology of irritable bowel syndrome involves a complex interaction of neurological, inflammatory, and immunological factors.
- Evidence suggests that patients with irritable bowel syndrome experience chronic inflammation.
- Intestinal immune factors may influence the central nervous system responses in irritable bowel syndrome.
- The microbiota plays a role in the brain-gut axis, which may contribute to chronic inflammation in these patients.
- Interactions between the immune system, brain, and gut are clinically relevant to the progression of irritable bowel syndrome.
Simplified
Key numbers
9–16%
Population Prevalence
Percentage of the population affected by , with higher rates in females.
50%
Immune Cell Activation
Proportion of patients showing increased immune cell presence in the lamina propria.