Lysosomal Membrane Proteins: Key Regulators of Glucose Metabolism and Its Associated Diseases

Apr 10, 2026FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Lysosomal Membrane Proteins as Important Controllers of Sugar Metabolism and Related Diseases

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Abstract

Lysosomal membrane proteins (LMPs) are central to regulating glucose metabolism.

  • LMPs are involved in key processes such as glycogen metabolism, glycolysis, and gluconeogenesis.
  • The review highlights the potential impact of LMPs on glucose homeostasis.
  • LMPs may influence metabolic diseases through the regulation of autophagy and signaling networks.
  • A deeper understanding of LMPs could reveal their significant contribution to lysosomal function in disease development.

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