The lancet. Diabetes & endocrinology

Mazdutide's safety and effectiveness in US adults with obesity or overweight: a phase 2 clinical trial

Updated

Abstract

Mazdutide, a dual agonist targeting glucagon and GLP-1 receptors, is evaluated for weight reduction in adults with obesity or overweight.

  • Mazdutide may provide effective weight loss in adults with obesity or overweight.
  • The study investigates doses of mazdutide up to 16 mg.
  • Safety and tolerability are key components of the evaluation.
  • Participants did not have type 2 diabetes.

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