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Abstract
AMP-activated protein kinase (AMPK) is a central energy sensor that maintains systemic lipid homeostasis.
- AMPK plays a crucial role in regulating lipid balance through various metabolic pathways.
- It may suppress the creation of new fat, enhance the breakdown of fatty acids, and modulate cholesterol metabolism.
- AMPK is involved in promoting cellular processes like autophagy and lipophagy.
- The review highlights the tissue-specific regulatory functions of AMPK in organs such as the liver, adipose tissue, and skeletal muscle.
- There is ongoing exploration of AMPK-targeting agents, including both natural products and synthetic compounds, for their potential therapeutic uses.
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