Melatonin in Circadian Rhythm and Brain Health: Neuroprotective Effects and Therapeutic Potential

Melatonin may positively affect brain health through multiple pathways.

• Melatonin regulates circadian rhythms and has antioxidant, anti-inflammatory, and immunomodulatory properties.
• Evidence suggests melatonin could be beneficial in conditions such as Alzheimer's disease and Parkinson's disease.
• Many observed benefits derive from small clinical trials or animal studies, necessitating further validation.
• The strength of evidence for melatonin's effects varies across different brain health conditions.
• Obtaining melatonin from food and dietary supplements is suggested as a safe option for consumers.

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