Melatonin as a mitochondrial protector in neurodegenerative diseases

Aug 10, 2017Cellular and molecular life sciences : CMLS

Melatonin's role in protecting energy producers in brain cells during neurodegenerative diseases

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Abstract

Mitochondrial dysfunction is a primary event in neurodegeneration.

  • Melatonin may exert protective roles on mitochondria, which are essential for energy production in brain cells.
  • Disturbances in mitochondrial physiology are associated with neurodegenerative conditions such as Alzheimer's, Parkinson's, and Huntington's diseases.
  • Melatonin's antioxidant properties could play a significant role in mitigating the effects of neurodegeneration.
  • The neuroprotective effects of melatonin are potentially more effective during the early stages of neurodegenerative diseases.

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