Mechanisms of ageing and development

Metformin treatment may increase immune cell aging markers and longevity genes in Asian Indians with prediabetes over 24 weeks

Updated

Abstract

Asian Indians show high rates of prediabetes progression to type 2 diabetes, associated with accelerated biological aging.

  • Prediabetes progression to type 2 diabetes is notably prevalent among Asian Indians.
  • Accelerated biological aging may play a role in this increased risk.
  • Metformin is suggested to have potential anti-aging effects that are not solely linked to its role in managing blood sugar levels.
  • Randomized controlled trials focused on telomere biology in prediabetes populations are currently insufficient.

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