Microbiota y diabetes mellitus tipo 2

Obesity is associated with changes in the gut microbiome composition, particularly an overgrowth of microorganisms that more efficiently extract energy from food.

• Alterations in gut microbiota may contribute to the onset of insulin resistance and diabetes.
• Mechanisms linking microbiota to metabolic disorders include increased bowel permeability and endotoxemia.
• Interactions with bile acids and changes in brown adipose tissue proportions may also play a role.
• The use of probiotics, prebiotics, and gut microbiota transplants is being explored as potential strategies to influence obesity and insulin resistance.
• Antibiotic therapy has been suggested as another approach to modulating gut microbiome effects on metabolism.

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