Treating Alzheimer's and Parkinson’s by targeting the gut-brain connection: recent therapy approaches

Altered gut microbiota composition may be associated with neuroinflammation and neurodegeneration in Alzheimer's and Parkinson's diseases.

• The microbiota-gut-brain axis facilitates communication between the gut and the central nervous system.
• Impaired barrier integrity in the gut could contribute to neuroinflammation.
• Dysregulated metabolite production may influence the progression of neurodegenerative disorders.
• Immune activation in the gut is linked to neurodegeneration.

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