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Abstract
Endothelial and microvascular dysfunction are key features of Long COVID.
- Altered cellular redox balance may contribute to vascular impairment in Long COVID.
- Changes in NAD+/NADH dynamics are observed in individuals with Long COVID.
- Flow-Mediated Skin Fluorescence (FMSF) is used to assess microvascular function through NADH fluorescence during blood flow changes.
- The study integrates FMSF with targeted NAD+ metabolite profiling to explore associations with microvascular responses.
- Impaired microvascular responses may be linked to alterations in NAD+ metabolism.
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