How mitochondrial self-cleaning links two types of cell death in lung cancer

Lung cancer is associated with extremely high morbidity and fatality rates among malignant tumors.

• Mitochondrial autophagy plays a crucial role in maintaining mitochondrial quality control.
• New forms of cell death, such as ferroptosis and cuproptosis, are linked to mitochondrial autophagy.
• Understanding the interactions among mitochondrial autophagy, ferroptosis, and cuproptosis may provide insights for lung cancer management.
• The review explores molecular mechanisms that could serve as therapeutic targets for precision lung cancer treatment.

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