European journal of clinical investigation

Mitochondrial DNA Levels and Related Genes in Sudden and Stable Heart Artery Disease

Updated

Abstract

Mitochondrial DNA copy number (mtDNA-CN) is investigated in patients with stable angina and acute coronary syndrome.

  • Mitochondrial dysfunction is linked to coronary artery disease (CAD).
  • The relationship between mtDNA-CN and mitochondrial homeostasis in CAD presentations is not well understood.
  • Key regulators involved in mitochondrial biogenesis and mitophagy are assessed alongside mtDNA-CN.
  • Patients with stable angina and acute coronary syndrome are the focus of this investigation.

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