Chinese medical journal

Updates on How Cells Maintain Healthy Mitochondria in Health and Disease

Updated

Abstract

Dysregulation of mitochondrial quality control is closely associated with various diseases, including neurodegenerative disorders and cancers.

  • Mitochondrial quality control involves mechanisms such as mitochondrial biogenesis and mitophagy that are essential for cellular function.
  • Abnormalities in mitochondrial quality control may contribute to the development of diseases like cardiovascular and kidney diseases.
  • Current understanding of the molecular regulation of mitochondrial quality control remains incomplete and complex.
  • Potential therapeutic targets for restoring mitochondrial quality control are being explored to address associated diseases.
  • Emerging treatment strategies aim to optimize mitochondrial function, offering insights for future disease management.

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