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Molecular Circadian Rhythms in Central and Peripheral Clocks in Mammals
Daily molecular rhythms in the brain's central clock and body clocks in mammals
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Abstract
Recent discoveries highlight the complexity of the circadian clock mechanism, involving numerous clock components and regulatory processes.
- New clock components have been identified, enhancing the understanding of circadian rhythm organization.
- Transcription may not be the primary determinant in clock function, suggesting alternative regulatory mechanisms.
- Post-translational modifications of clock proteins introduce additional levels of control over circadian rhythms.
- Chromatin remodeling is crucial for regulating the expression of key components of the circadian clock.
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