Molecular therapy : the journal of the American Society of Gene Therapy

New Technologies for Delivering Therapeutic mRNA Treatments

Updated

Abstract

Current clinical efforts in mRNA therapeutics focus on vaccination, protein replacement therapies, and treatment of genetic diseases.

  • mRNA has significant potential as a therapeutic approach.
  • Advances in mRNA manufacturing and delivery methods have enabled clinical translation.
  • Challenges remain in achieving broad application due to the need for improved delivery systems.
  • Recent advances in biomaterials and delivery strategies are being explored to enhance mRNA-based therapeutics.
  • Applications of mRNA delivery include protein therapy, gene editing, and vaccination.

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