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Using Multiple Biological Measures to Profile Immune Changes in Human Aging
Updated
Abstract
Midlife (aged 55-65) immune remodeling is revealed through multi-omic profiling and longitudinal influenza vaccination.
- Peripheral immune aging was mapped using a combination of blood cell analysis, protein profiling, and cell function assessments.
- Early signs of immune dysregulation were observed prior to the aging process.
- Links to increased disease susceptibility were identified before the onset of chronic inflammation associated with aging.
Simplified
Longevity & Aging