Exploring factors associated with the intensity of a mystical experience following naturalistic psychedelic use: A retrospective survey

A total of 1657 participants were included in the analysis of factors associated with mystical experience intensity during naturalistic psychedelic use.

• The main motive for the psychedelic experience significantly influences mystical experience intensity, with spiritual/religious, therapeutic, and self-exploration motives having a greater impact than recreational use.
• Different psychedelic substances affect mystical experience intensity differently, with Ayahuasca and lysergic acid diethylamide showing greater effects compared to psilocybin.
• Higher subjective dosage levels are associated with more intense mystical experiences, particularly when comparing very high, high, and moderate doses to very low doses.
• The number of psychedelic sessions and the time elapsed since the experience also correlate with the intensity of mystical experiences.
• Concomitant alcohol use is linked to less intense psychedelic experiences, suggesting the importance of screening for substance use in research contexts.

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