Cardiovascular research

Restoring NAD+ lowers heart muscle aging and improves heart relaxation in older men

Updated

Abstract

NAD+ replenishment may regulate cardiomyocyte senescence and cardiac function in aging.

  • Cardiomyocyte senescence is linked to diastolic dysfunction and heart failure in older adults.
  • Effective strategies to delay or reverse this senescence in the aged heart are currently limited.
  • The study investigates the potential role of NAD+ replenishment in influencing cardiomyocyte aging.
  • Preliminary findings suggest that NAD+ levels could impact heart cell health and function.

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