Natural plant sugars as treatments for Alzheimer's disease: How they work, their structures, and potential for use

Alzheimer's disease (AD) is linked to multiple interconnected factors including amyloid-β deposition and tau pathology.

• AD is characterized by amyloid-β deposition, tau pathology, oxidative stress, and mitochondrial dysfunction.
• Neuroinflammation and synaptic impairment are also associated with the progression of AD.
• Dysregulation of the microbiota-gut-brain axis may contribute to the disorder.
• Natural polysaccharides have been noted for their potential anti-AD effects but are typically discussed in isolation rather than as part of an integrated framework.

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