Frontiers in pharmacology

Natural products affecting mitochondrial balance through movement, recycling, drug behavior, and safety

Updated

Abstract

Dysregulated mitochondrial dynamics is associated with the pathogenesis of many diseases.

  • Mitochondrial functions such as fission, fusion, biogenesis, and mitophagy are crucial to cellular health.
  • Natural products may offer multi-target therapeutic options for various diseases.
  • Current knowledge gaps regarding the mechanisms of action of natural products limit their clinical applications.
  • Pharmacokinetic limitations of natural products could impact their effectiveness in treatment.

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