Highly reconfigurable neuronlike conductive networks through nanophase structure engineering

Dec 30, 2025Nature communications

Easily adjustable neuron-like conductive networks created by engineering tiny structures

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Regenerative Health on OpenScience ↗PubMed ↗DOI ↗OA ↗

Abstract

A methodology of reversible nanophase regulation could successfully integrate multiple traditionally contradictory properties in bionic electronics.

The system combines outstanding electrical and mechanical performance with excellent reconfigurability.
It allows for the re-writability of conductive pathways and in-situ wet solderability with good spatial resolution.
Closed-loop recyclability is achieved, addressing environmental concerns in electronic waste.
Dynamic responses to specific ions may enhance the adaptability of devices in biological environments.

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Bionic electronics are designed to bridge the gap between biological systems and conventional electronic devices. However, replicating the high dynamic adaptivity and functional plasticity of living tissues while preserving the electrical performance and structural integrity of traditional electronics remains highly challenging, owing to the intrinsic trade-offs in molecular design. To address this issue, a methodology of reversible nanophase regulation is proposed, inspired by ion-specific effects in biological environments. Benefiting from the dynamic response of noncovalent interaction to specific ions, the developed system can successfully integrate multiple traditionally contradictory properties-combining outstanding electrical/mechanical performance with excellent reconfigurability, such as re-writability of conductive pathways, in-situ wet solderability with good spatial resolution, and closed-loop recyclability. This methodology offers a promising framework for designing reconfigurable devices for bioelectronics applications such as human-machine integration and tissue engineering.

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Highly reconfigurable neuronlike conductive networks through nanophase structure engineering

Abstract

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