JAMA

Nicotinamide Riboside Treatment in Early Parkinson’s Disease: A Randomized Clinical Trial

Updated

Abstract

Nicotinamide riboside has been proposed as a potential disease-modifying therapy for Parkinson disease.

  • Nicotinamide riboside is a precursor to nicotinamide adenine dinucleotide.
  • Preclinical and early studies suggest it may have therapeutic potential in Parkinson disease.
  • The effect of prolonged oral nicotinamide riboside on clinical outcomes in Parkinson disease is currently unknown.

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