Advances in nucleic acid therapeutics: structures, delivery systems, and future perspectives in cancer treatment

Aug 28, 2024Clinical and experimental medicine

New developments in genetic therapies: structures, delivery methods, and future options for cancer treatment

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Abstract

may offer new possibilities for tumor remission and cure.

  • Nucleic acid drugs regulate gene expression by introducing exogenous nucleic acid fragments.
  • Their high specificity could enhance treatment outcomes in cancer therapy.
  • Challenges include low stability and limited ability to cross physiological barriers in the body.
  • Various delivery vectors have been developed to improve stability and targeted delivery of these drugs.
  • The review discusses the structures and principles of nucleic acid drugs and their cellular uptake processes.
  • Research progress and applications of nucleic acid drug delivery vectors are highlighted, along with future trends.

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