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Nutritional Management of Schizophrenia: Gut-Brain Axis Mechanisms and Dietary Interventions
How Diet May Influence Schizophrenia Through Gut-Brain Connections
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Abstract
Approximately 1% of the global population is affected by schizophrenia (SCZ), a complex mental disorder.
- Schizophrenia involves interactions among genetic, environmental, and lifestyle factors, including diet and stress.
- Clozapine is recognized as the most effective antipsychotic for treatment-resistant SCZ patients.
- Nutritional interventions and lifestyle modifications may play a crucial role in managing SCZ.
- Dysbiosis, or altered gut microbiota composition, is linked to neuroinflammation and neurotransmitter imbalances relevant to SCZ.
- Maternal nutrition during pregnancy can impact fetal neurodevelopment and may predispose offspring to SCZ.
- High consumption of fast food and processed carbohydrates among individuals with SCZ may worsen nutritional deficiencies and gut microbiota dysregulation.
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