Unravelling the nutritional threads with novel associations of cognitive functions and telomerase

Dec 4, 2025Nutrition research reviews

New Links Between Nutrition, Thinking Skills, and Cell Aging Enzyme

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Abstract

Leucocyte telomere length (LTL) may be linked to cognitive outcomes in brain ageing.

  • Long-chain omega-3 polyunsaturated fatty acids (PUFA) could influence telomere biology and cognitive function.
  • Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are associated with anti-inflammatory and antioxidant effects.
  • Variability in findings across different cohorts suggests that the relationship between LTL and cognition is complex.
  • Biological mechanisms such as oxidative stress, inflammation, and mitochondrial function may be involved in telomere attrition.
  • Future studies should prioritize clarifying the causal pathways linking omega-3 PUFA, telomere length, and cognitive health.

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