[The nyctohemeral rhythm of melatonin is preserved in human African trypanosomiasis].
The daily cycle of melatonin stays normal in human African sleeping sickness
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Abstract
In a study involving nine patients with human African trypanosomiasis, plasma melatonin profiles were similar to those of six healthy controls.
- The sleep-wake cycle showed disturbances correlated with the severity of the disease.
- Plasma melatonin levels did not differ significantly between patients and healthy individuals.
- These findings imply the potential involvement of an additional system regulating melatonin rhythms beyond the main circadian clock.
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