Obstructive sleep apnoea, resistant hypertension and renal denervation

Jun 5, 2013EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Obstructive sleep apnea, hard-to-treat high blood pressure, and kidney nerve treatment

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Abstract

Obstructive sleep apnoea (OSA) was diagnosed in 64% of patients with resistant hypertension.

  • Sleep apnoea affects 5% to 10% of the general population.
  • OSA is the most prevalent condition linked to resistant hypertension.
  • OSA is associated with an increased risk of cardiovascular events, including heart disease, heart failure, stroke, and death.
  • Potential mechanisms for the link between OSA and cardiovascular disease include oxidative stress, inflammation, and dysfunction of blood vessel lining.
  • Continuous positive airway pressure (CPAP) is an effective treatment for severe OSA and its related health risks.

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