Connections between Mouth Bacteria and Mental Health: A Review

A reproducible signature of the oral microbiome shows enriched Prevotella and depleted Haemophilus and Rothia.

• The oral microbiome may influence the gut-brain axis and its associated mental health conditions.
• Four pathways link an imbalanced oral microbiome to potential brain inflammation and dysregulation of neurotransmitter signaling.
• The connection between oral health and mental health suggests that dental visits could serve as opportunities for screening and prevention.
• Dysbiosis in the mouth could be associated with broader implications for mental health management.

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