Association between the Oxytocin Receptor Gene Polymorphism (rs53576) and Bulimia Nervosa

Mar 17, 2015European eating disorders review : the journal of the Eating Disorders Association

Link between a common oxytocin receptor gene variant and bulimia nervosa

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Abstract

A positive association exists between the G allele of OXTR rs53576 and bulimia nervosa in a study of 90 patients.

  • The study involved 262 women, including 69 with anorexia nervosa and 90 with bulimia nervosa.
  • Genetic variants in the oxytocin receptor gene may play a role in eating disorders.
  • G allele carriers of OXTR rs53576 in the bulimia nervosa group exhibited higher scores on the behavioral inhibition system.
  • Findings indicate a potential link between the oxytocinergic system and bulimia nervosa.

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