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Abstract
Over 25% of the global population is affected by metabolic dysfunction-associated fatty liver disease (MASLD).
- Pannexin 1 (Panx1) may play a role in metabolic regulation related to liver health.
- The specific involvement of Panx1 in liver fat metabolism has not been previously studied.
- There is a hypothesis that Panx1 regulates the AMPK-autophagy axis, which could influence liver fat buildup and insulin sensitivity.
Simplified