Plastic and reconstructive surgery

Partial Cell Reprogramming as a New Approach in Plastic Surgery

Updated

Abstract

Partial cellular reprogramming is set to enter a first in-human trial in 2026 for optic neuropathy and glaucoma.

  • Partial cellular reprogramming uses Yamanaka factors to revert aging cells to a younger state while maintaining their original function.
  • This approach has evolved over more than twenty years from laboratory research to clinical application.
  • The intersection of partial cellular reprogramming and plastic surgery may lead to innovative applications in treating age-related conditions.

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