JAMA network open

Patient Experiences Using GLP-1 Receptor Agonist Medications

Updated

Abstract

Of 30 participants, 23 were using a GLP-1 receptor agonist at the time of the interview.

  • Participants reported a reduction in food-related thoughts and appetite while using GLP-1 receptor agonists.
  • Many indicated that GLP-1 receptor agonists alone are not sufficient for weight loss.
  • A wide range of adverse effects was experienced by participants, with some willing to endure significant challenges for weight loss.
  • Stigma was perceived by patients based on the primary reason for their GLP-1 RA prescription.
  • The provision of information and clinical support was found to be inconsistent among participants.
  • Challenges related to access and cost were identified as significant barriers to treatment.
  • Participants valued shared experiences, highlighting the importance of community support.

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Funding

Competing interests

Conflict of Interest Disclosures: Dr Rodriguez reported receiving grants from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute and from the Doris Duke Foundation during the conduct of the study; and receiving personal fees from Novartis, Novo Nordisk, Esperion Therapeutics, Movano Health, Kento Health, Edwards Lifesciences, Arrowhead Pharmaceuticals, HeartFlow, iRhythm, Amgen, and Cleerly Health outside the submitted work. No other disclosures were reported.
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