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Abstract
Essence
In children and young people, long COVID was linked to broad immune dysregulation, weaker anti-SARS-CoV-2 antibodies, and lower neutralizing capacity.
Evidence
This 3-month immune profiling comparison studied PBMC compartments and SARS-CoV-2 antibody responses in 99 children and young people with long COVID versus 18 without, with myeloid CCR6 expression distinguishing groups at 79% accuracy.
Caveat
This was a single post-infection observational comparison with a small control group, so the biomarker signal does not show causation or broader diagnostic performance.
Simplified
Long Covid