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Perioperative management of long-acting glucagon-like peptide-1 (GLP-1) receptor agonists: concerns for delayed gastric emptying and pulmonary aspiration
Managing long-acting GLP-1 diabetes drugs around surgery: risks of slow stomach emptying and lung aspiration
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Abstract
Prescriptions for glucagon-like peptide-1 (GLP-1) receptor agonists are increasing dramatically as indications expand beyond diabetes treatment to weight loss for people with obesity.
- GLP-1 receptor agonists are known to delay gastric emptying.
- The impact of ongoing treatment on gastric emptying is that it may lessen this delay.
- The risk of pulmonary aspiration during general anaesthesia for patients on GLP-1 receptor agonists is currently unknown.
- Caution is advised for patients who have recently started GLP-1 receptor agonist treatment.
- For patients treated with GLP-1 receptor agonists for over 12 weeks, standard fasting times may be adequate to manage aspiration risk in most low-risk cases.
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