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Perioperative and periprocedural management of GLP-1 receptor-based agonists and SGLT2 inhibitors: narrative review and the STOP-GAP and STOP DKA-2 algorithms
Managing GLP-1 and SGLT2 diabetes medicines around surgery using the STOP-GAP and STOP DKA-2 guidelines
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Abstract
GLP-1 receptor-based agonists (GLP-1RAs) and SGLT2 inhibitors (SGLT2i) may pose significant perioperative and periprocedural risks.
- GLP-1RAs are linked to an increased risk of retained gastric contents.
- Pulmonary aspiration is a potential complication associated with GLP-1RA use.
- SGLT2 inhibitors may increase the risk of diabetic ketoacidosis during surgical procedures.
- Recommendations and algorithms are provided for the safe management of patients using these medications in perioperative settings.
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