How Serotonin Outside the Brain May Affect COVID-19 Infection, Treatment, and Long-Term Symptoms

Gastrointestinal symptoms such as diarrhea and nausea are common in SARS-CoV-2 infection.

• Gastrointestinal symptoms are frequently reported in COVID-19 cases and may contribute to overall morbidity.
• The gastrointestinal tract may serve as a potential entry point for the virus, possibly affecting disease progression.
• SARS-CoV-2 infection may influence gut-derived serotonin levels, which could be linked to associated symptoms.
• There is a potential connection between serotonin levels and the effectiveness of selective serotonin reuptake inhibitors in managing COVID-19 severity.

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